A Placebo-Controlled Trial of Dextromethorphan as an Adjunct in Opioid-Dependent Patients Undergoing Methadone Maintenance Treatment

BACKGROUND: Low-dose dextromethorphan (DM) might have anti-inflammatory and neurotrophic effects mechanistically remote from an NMDA receptor. In a randomized, double-blind, controlled 12 week study, we investigated whether add-on dextromethorphan reduced cytokine levels and benefitted opioid-depend...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Lee, Sheng-Yu, Chen, Shiou-Lan, Chang, Yun-Hsuan, Chu, Chun-Hsien, Chen, Shih-Heng, Chen, Po See, Huang, San-Yuan, Tzeng, Nian-Sheng, Wang, Liang-Jen, Lee, I Hui, Wang, Tzu-Yun, Chen, Kao Chin, Yang, Yen Kuang, Hong, Jau-Shyong, Lu, Ru-Band
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540107/
https://ncbi.nlm.nih.gov/pubmed/25716777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyv008
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