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Disproportionate Reduction of Serotonin Transporter May Predict the Response and Adherence to Antidepressants in Patients with Major Depressive Disorder: A Positron Emission Tomography Study with 4-[(18)F]-ADAM

BACKGROUND: Many lines of evidence suggest the role of serotonin transporter (SERT)-mediated reuptake of serotonin in the pathophysiology and treatment of major depressive disorder (MDD). This study aimed to examine whether the pretreatment of SERT binding potential or SERT binding ratio between ter...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Neuropsychopharmacol
Hauptverfasser: Yeh, Yi-Wei, Ho, Pei-Shen, Kuo, Shin-Chang, Chen, Chun-Yen, Liang, Chih-Sung, Yen, Che-Hung, Huang, Chang-Chih, Ma, Kuo-Hsing, Shiue, Chyng-Yann, Huang, Wen-Sheng, Shyu, Jia-Fwu, Wan, Fang-Jung, Lu, Ru-Band, Huang, San-Yuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540099/
https://ncbi.nlm.nih.gov/pubmed/25568284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyu120
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