Allantoin ameliorates chemically-induced pancreatic β-cell damage through activation of the imidazoline I3 receptors

Objective. Allantoin is the primary active compound in yams (Dioscorea spp.). Recently, allantoin has been demonstrated to activate imidazoline 3 (I3) receptors located in pancreatic tissues. Thus, the present study aimed to investigate the role of allantoin in the effect to improve damage induced i...

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Detalles Bibliográficos
Publicado en:PeerJ
Autores principales: Amitani, Marie, Cheng, Kai-Chun, Asakawa, Akihiro, Amitani, Haruka, Kairupan, Timothy Sean, Sameshima, Nanami, Shimizu, Toshiaki, Hashiguchi, Teruto, Inui, Akio
Formato: Artigo
Lenguaje:Inglês
Publicado: PeerJ Inc. 2015
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540048/
https://ncbi.nlm.nih.gov/pubmed/26290782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.1105
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