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Rosmarinic acid ameliorates hyperglycemia and insulin sensitivity in diabetic rats, potentially by modulating the expression of PEPCK and GLUT4

BACKGROUND: Rosmarinic acid (RA) is a natural substance that may be useful for treating diabetes mellitus. The present study investigated the effects of RA on glucose homeostasis and insulin regulation in rats with streptozocin (STZ)-induced type 1 diabetes or high-fat diet (HFD)-induced type 2 diab...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Runtuwene, Joshua, Cheng, Kai-Chun, Asakawa, Akihiro, Amitani, Haruka, Amitani, Marie, Morinaga, Akinori, Takimoto, Yoshiyuki, Kairupan, Bernabas Harold Ralph, Inui, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940010/
https://ncbi.nlm.nih.gov/pubmed/27462144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S108539
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