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MicroRNA-7/NF-κB signaling regulatory feedback circuit regulates gastric carcinogenesis

MicroRNAs play essential roles in gene expression regulation during carcinogenesis. Here, we investigated the role of miR-7 and the mechanism by which it is dysregulated in gastric cancer (GC). We used genome-wide screenings and identified RELA and FOS as novel targets of miR-7. Overexpression of mi...

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Dades bibliogràfiques
Publicat a:J Cell Biol
Autors principals: Zhao, Xiao-Di, Lu, Yuan-Yuan, Guo, Hao, Xie, Hua-Hong, He, Li-Jie, Shen, Gao-Fei, Zhou, Jin-Feng, Li, Ting, Hu, Si-Jun, Zhou, Lin, Han, Ya-Nan, Liang, Shu-Li, Wang, Xin, Wu, Kai-Chun, Shi, Yong-Quan, Nie, Yong-Zhan, Fan, Dai-Ming
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539989/
https://ncbi.nlm.nih.gov/pubmed/26261179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201501073
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