FrzA gene protects cardiomyocytes from H(2)O(2)-induced oxidative stress through restraining the Wnt/Frizzled pathway

BACKGROUND: Lately, there is accumulating evidence that the Wnt/Frizzled pathway is reactivated after myocardial infarction, the inhibition of the pathway is beneficial since it reduce of myocardial apoptosis and prevents heart failure. FrzA/Sfrp-1, a secreted frizzled-related protein and antagonist...

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Detalhes bibliográficos
Publicado no:Lipids Health Dis
Main Authors: Tao, Jing, Chen, Bang-dang, Ma, Yi-tong, Yang, Yi-ning, Li, Xiao-mei, Ma, Xiang, Yu, Zi-xiang, Liu, Fen, Xiang, Yang, Chen, You
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539933/
https://ncbi.nlm.nih.gov/pubmed/26282432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-015-0088-0
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