Frizzled-8 receptor is activated by the Wnt-2 ligand in non-small cell lung cancer

BACKGROUND: Wnt-2 plays an oncogenic role in cancer, but which Frizzled receptor(s) mediates the Wnt-2 signaling pathway in lung cancer remains unclear. We sought to (1) identify and evaluate the activation of Wnt-2 signaling through Frizzled-8 in non-small cell lung cancer, and (2) test whether a n...

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Main Authors: Bravo, Dawn T, Yang, Yi-Lin, Kuchenbecker, Kristopher, Hung, Ming-Szu, Xu, Zhidong, Jablons, David M, You, Liang
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707790/
https://ncbi.nlm.nih.gov/pubmed/23815780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-316
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