Targeting Filarial Abl-like Kinases: Orally Available, Food and Drug Administration–Approved Tyrosine Kinase Inhibitors Are Microfilaricidal and Macrofilaricidal

Background. Elimination of onchocerciasis and lymphatic filariasis is targeted for 2020. Given the coincident Loa loa infections in Central Africa and the potential for drug resistance development, the need for new microfilaricides and macrofilaricides has never been greater. With the genomes of L....

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Sparad:
Bibliografiska uppgifter
I publikationen:J Infect Dis
Huvudupphovsmän: O'Connell, Elise M., Bennuru, Sasisekhar, Steel, Cathy, Dolan, Michael A., Nutman, Thomas B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Major Articles and Brief Reports
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539898/
https://ncbi.nlm.nih.gov/pubmed/25657255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv065
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