Porcine epidemic diarrhea virus inhibits dsRNA-induced interferon-β production in porcine intestinal epithelial cells by blockade of the RIG-I-mediated pathway

BACKGROUND: The lack of optimal porcine cell lines has severely impeded the study and progress in elucidation of porcine epidemic diarrhea virus (PEDV) pathogenesis. Vero cell, an African green monkey kidney cell line, was often used to isolate and propagate PEDV. Nonetheless, the target cells of PE...

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Publicado en:Virol J
Autores principales: Cao, Liyan, Ge, Xuying, Gao, Yu, Herrler, Georg, Ren, Yudong, Ren, Xiaofeng, Li, Guangxing
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539884/
https://ncbi.nlm.nih.gov/pubmed/26283628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-015-0345-x
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