Pharmacokinetics and distributions of bevacizumab by intravitreal injection of bevacizumab-PLGA microspheres in rabbits

AIM: To investigate the pharmacokinetics and distributions of bevacizumab by intravitreal injection of prepared bevacizumab-poly (L-lactic-co-glycolic acid) (PLGA) microspheres in rabbits, to provide evidence for clinical application of this kind of bevacizumab sustained release dosage form. METHODS...

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Vydáno v:Int J Ophthalmol
Hlavní autoři: Ye, Zhuo, Ji, Yan-Li, Ma, Xiang, Wen, Jian-Guo, Wei, Wei, Huang, Shu-Man
Médium: Artigo
Jazyk:Inglês
Vydáno: International Journal of Ophthalmology Press 2015
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539635/
https://ncbi.nlm.nih.gov/pubmed/26309857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3980/j.issn.2222-3959.2015.04.02
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