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Systemic modeling myeloma-osteoclast interactions under normoxic/hypoxic condition using a novel computational approach
Interaction of myeloma cells with osteoclasts (OC) can enhance tumor cell expansion through activation of complex signaling transduction networks. Both cells reside in the bone marrow, a hypoxic niche. How OC-myeloma interaction in a hypoxic environment affects myeloma cell growth and their response...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4539608/ https://ncbi.nlm.nih.gov/pubmed/26282073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13291 |
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