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Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion

Survivin promotes cell division and suppresses apoptosis in many human cancers, and increased abundance correlates with metastasis and poor prognosis. Here, we showed that a pool of survivin that localized to the mitochondria of certain tumor cell lines enhanced the stability of oxidative phosphoryl...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Rivadeneira, Dayana B., Caino, M. Cecilia, Seo, Jae Ho, Angelin, Alessia, Wallace, Douglas C., Languino, Lucia R., Altieri, Dario C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539531/
https://ncbi.nlm.nih.gov/pubmed/26268608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aab1624
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