(C-A)n microsatellite repeat D7S522 is the most commonly deleted region in human primary breast cancer.
Loss of heterozygosity in human chromosome 7q was studied to determine the location of a putative tumor suppressor gene. Twenty-six of 31 cases studied presented loss of heterozygosity at one or more loci on chromosome 7q. Eighty-three percent loss of heterozygosity (in 11 informative cases) was det...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1994
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45395/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7991599/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.25.12155 |
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