(C-A)n microsatellite repeat D7S522 is the most commonly deleted region in human primary breast cancer.

Loss of heterozygosity in human chromosome 7q was studied to determine the location of a putative tumor suppressor gene. Twenty-six of 31 cases studied presented loss of heterozygosity at one or more loci on chromosome 7q. Eighty-three percent loss of heterozygosity (in 11 informative cases) was det...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Zenklusen, J C, Bièche, I, Lidereau, R, Conti, C J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45395/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7991599/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.25.12155
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