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Characterizing Methyl-Bearing Side Chain Contacts and Dynamics Mediating Amyloid β Protofibril Interactions Using (13)C(methyl)-DEST and Lifetime Line Broadening()
Many details pertaining to the formation and interactions of protein aggregates associated with neurodegenerative diseases are invisible to conventional biophysical techniques. We recently introduced (15)N dark-state exchange saturation transfer (DEST) and (15)N lifetime line-broadening to study sol...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4539159/ https://ncbi.nlm.nih.gov/pubmed/25130489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201405180 |
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