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Signaling mechanisms coupled to CXCL12/CXCR4-mediated cellular proliferation are PTEN-dependent
A key difference between normal and malignant prostate cells in vitro and in vivo is that both alleles of PTEN are largely intact in normal benign prostate glands and cultured epithelial cells, whereas one or both alleles of PTEN are mutant or deleted in the majority of prostate tumors and malignant...
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| Published in: | Am J Clin Exp Urol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
e-Century Publishing Corporation
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4539110/ https://ncbi.nlm.nih.gov/pubmed/26309898 |
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