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Signaling mechanisms coupled to CXCL12/CXCR4-mediated cellular proliferation are PTEN-dependent

A key difference between normal and malignant prostate cells in vitro and in vivo is that both alleles of PTEN are largely intact in normal benign prostate glands and cultured epithelial cells, whereas one or both alleles of PTEN are mutant or deleted in the majority of prostate tumors and malignant...

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Detalhes bibliográficos
Publicado no:Am J Clin Exp Urol
Main Authors: Begley, Lesa A, Kasina, Sathish, Shah, Rajal B, Macoska, Jill A
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539110/
https://ncbi.nlm.nih.gov/pubmed/26309898
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