Identification of novel mutations associated with clofazimine resistance in Mycobacterium tuberculosis

OBJECTIVES: Although clofazimine has been traditionally used to treat leprosy, there is recent interest in using clofazimine for the treatment of MDR-TB and drug-susceptible TB. However, the mechanisms of resistance to clofazimine are poorly understood. Here, we investigated the molecular basis of c...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Antimicrob Chemother
Main Authors: Zhang, Shuo, Chen, Jiazhen, Cui, Peng, Shi, Wanliang, Zhang, Wenhong, Zhang, Ying
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539095/
https://ncbi.nlm.nih.gov/pubmed/26045528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkv150
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