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A polymorphism at the microRNA binding site in the 3′ untranslated region of RYR3 is associated with outcome in hepatocellular carcinoma

OBJECTIVE: MicroRNAs can bind to the 3′ untranslated regions (UTRs) of messenger RNAs, where they interfere with the translation of targeting genes, thereby regulating cell differentiation, apoptosis, and tumorigenesis. In this study, three microRNA binding site single nucleotide polymorphisms (SNPs...

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Publicado en:Onco Targets Ther
Main Authors: Peng, Chenxing, Guo, Zhanjun, Wu, Xiaoyan, Zhang, Xiao-lan
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539090/
https://ncbi.nlm.nih.gov/pubmed/26309413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S85856
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