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Effects of amoxicillin/clavulanic acid on the pharmacokinetics of valproic acid
Valproic acid (VPA) is mainly metabolized via glucuronide, which is hydrolyzed by β-glucuronidase and undergoes enterohepatic circulation. Amoxicillin/clavulanic acid (AMC) administration leads to decreased levels of β-glucuronidase-producing bacteria, suggesting that these antibiotics could interru...
Shranjeno v:
| izdano v: | Drug Des Devel Ther |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Dove Medical Press
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4539086/ https://ncbi.nlm.nih.gov/pubmed/26309401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S89464 |
| Oznake: |
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