Navigating the chemical space of dipeptidyl peptidase-4 inhibitors

This study represents the first large-scale study on the chemical space of inhibitors of dipeptidyl peptidase-4 (DPP4), which is a potential therapeutic protein target for the treatment of diabetes mellitus. Herein, a large set of 2,937 compounds evaluated for their ability to inhibit DPP4 was compi...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Shoombuatong, Watshara, Prachayasittikul, Veda, Anuwongcharoen, Nuttapat, Songtawee, Napat, Monnor, Teerawat, Prachayasittikul, Supaluk, Prachayasittikul, Virapong, Nantasenamat, Chanin
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539085/
https://ncbi.nlm.nih.gov/pubmed/26309399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S86529
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