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Navigating the chemical space of dipeptidyl peptidase-4 inhibitors
This study represents the first large-scale study on the chemical space of inhibitors of dipeptidyl peptidase-4 (DPP4), which is a potential therapeutic protein target for the treatment of diabetes mellitus. Herein, a large set of 2,937 compounds evaluated for their ability to inhibit DPP4 was compi...
שמור ב:
| הוצא לאור ב: | Drug Des Devel Ther |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Dove Medical Press
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4539085/ https://ncbi.nlm.nih.gov/pubmed/26309399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S86529 |
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