Therapeutic designed poly (lactic-co-glycolic acid) cylindrical oseltamivir phosphate-loaded implants impede tumor neovascularization, growth and metastasis in mouse model of human pancreatic carcinoma

Poly (lactic-co-glycolic acid) (PLGA) copolymers have been extensively used in cancer research. PLGA can be chemically engineered for conjugation or encapsulation of drugs in a particle formulation. We reported that oseltamivir phosphate (OP) treatment of human pancreatic tumor-bearing mice disrupte...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Hrynyk, Michael, Ellis, Jordon P, Haxho, Fiona, Allison, Stephanie, Steele, Joseph AM, Abdulkhalek, Samar, Neufeld, Ronald J, Szewczuk, Myron R
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539083/
https://ncbi.nlm.nih.gov/pubmed/26309402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S90170
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