Therapeutic targeting of Neu1 sialidase with oseltamivir phosphate (Tamiflu®) disables cancer cell survival in human pancreatic cancer with acquired chemoresistance

BACKGROUND: Resistance to drug therapy, along with high rates of metastasis, contributes to the low survival rate in patients diagnosed with pancreatic cancer. An alternate treatment for human pancreatic cancer involving targeting of Neu1 sialidase with oseltamivir phosphate (Tamiflu®) was investiga...

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Detalhes bibliográficos
Main Authors: O’Shea, Leah K, Abdulkhalek, Samar, Allison, Stephanie, Neufeld, Ronald J, Szewczuk, Myron R
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896323/
https://ncbi.nlm.nih.gov/pubmed/24470763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S55344
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