A carregar...
Quantitative analysis reveals how EGFR activation and downregulation are coupled in normal but not in cancer cells
Ubiquitination of the epidermal growth factor receptor (EGFR) that occurs when Cbl and Grb2 bind to three phosphotyrosine residues (pY1045, pY1068 and pY1086) on the receptor displays a sharp threshold effect as a function of EGF concentration. Here we use a simple modelling approach together with e...
Na minha lista:
| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538861/ https://ncbi.nlm.nih.gov/pubmed/26264748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8999 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|