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Caffeine inhibits gene conversion by displacing Rad51 from ssDNA
Efficient repair of chromosomal double-strand breaks (DSBs) by homologous recombination relies on the formation of a Rad51 recombinase filament that forms on single-stranded DNA (ssDNA) created at DSB ends. This filament facilitates the search for a homologous donor sequence and promotes strand inva...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538809/ https://ncbi.nlm.nih.gov/pubmed/26019181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv525 |
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