Improving small RNA-seq by using a synthetic spike-in set for size-range quality control together with a set for data normalization

There is an increasing interest in complementing RNA-seq experiments with small-RNA (sRNA) expression data to obtain a comprehensive view of a transcriptome. Currently, two main experimental challenges concerning sRNA-seq exist: how to check the size distribution of isolated sRNAs, given the sensiti...

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Foilsithe in:Nucleic Acids Res
Main Authors: Locati, Mauro D., Terpstra, Inez, de Leeuw, Wim C., Kuzak, Mateusz, Rauwerda, Han, Ensink, Wim A., van Leeuwen, Selina, Nehrdich, Ulrike, Spaink, Herman P., Jonker, Martijs J., Breit, Timo M., Dekker, Rob J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2015
Ábhair:
Methods Online
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538800/
https://ncbi.nlm.nih.gov/pubmed/25870415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv303
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