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A high-throughput imaging-based mapping platform for the systematic identification of gene positioning factors

Genomes are non-randomly arranged in the 3D space of the cell nucleus. Here we have developed HIPMap, a high-precision, high-throughput, automated fluorescent in situ hybridization imaging pipeline, for mapping of the spatial location of genome regions at large scale. High-throughput imaging positio...

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Bibliografische gegevens
Gepubliceerd in:Cell
Hoofdauteurs: Shachar, Sigal, Voss, Ty C., Pegoraro, Gianluca, Sciascia, Nicholas, Misteli, Tom
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538709/
https://ncbi.nlm.nih.gov/pubmed/26276637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.07.035
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