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Identification of Mammalian Protein Quality Control Factors by High-Throughput Cellular Imaging

Protein Quality Control (PQC) pathways are essential to maintain the equilibrium between protein folding and the clearance of misfolded proteins. In order to discover novel human PQC factors, we developed a high-content, high-throughput cell-based assay to assess PQC activity. The assay is based on...

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מידע ביבליוגרפי
Main Authors: Pegoraro, Gianluca, Voss, Ty C., Martin, Scott E., Tuzmen, Pinar, Guha, Rajarshi, Misteli, Tom
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282772/
https://ncbi.nlm.nih.gov/pubmed/22363705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031684
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