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Activity-dependent BDNF release via endocytic pathways is regulated by synaptotagmin-6 and complexin
Brain-derived neurotrophic factor (BDNF) is known to modulate synapse development and plasticity, but the source of synaptic BDNF and molecular mechanisms regulating BDNF release remain unclear. Using exogenous BDNF tagged with quantum dots (BDNF-QDs), we found that endocytosed BDNF-QDs were prefere...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538679/ https://ncbi.nlm.nih.gov/pubmed/26216953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511830112 |
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