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Activity-dependent BDNF release via endocytic pathways is regulated by synaptotagmin-6 and complexin

Brain-derived neurotrophic factor (BDNF) is known to modulate synapse development and plasticity, but the source of synaptic BDNF and molecular mechanisms regulating BDNF release remain unclear. Using exogenous BDNF tagged with quantum dots (BDNF-QDs), we found that endocytosed BDNF-QDs were prefere...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Wong, Yu-Hui, Lee, Chia-Ming, Xie, Wenjun, Cui, Bianxiao, Poo, Mu-ming
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538679/
https://ncbi.nlm.nih.gov/pubmed/26216953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1511830112
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