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Synaptotagmin-IV Modulates Synaptic Function and LTP by Regulating BDNF Release

Synaptotagmin-IV (syt-IV) is a membrane trafficking protein that influences learning and memory, but its localization and role in synaptic function remain unclear. Here we discovered that syt-IV localizes to BDNF-containing vesicles in hippocampal neurons. Syt-IV/BDNF-harboring vesicles undergo exoc...

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Detalhes bibliográficos
Main Authors: Dean, Camin, Liu, Huisheng, Dunning, F. Mark, Chang, Payne Y., Jackson, Meyer B., Chapman, Edwin R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846764/
https://ncbi.nlm.nih.gov/pubmed/19448629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2315
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