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Molecular structure of monomorphic peptide fibrils within a kinetically trapped hydrogel network

Most, if not all, peptide- and protein-based hydrogels formed by self-assembly can be characterized as kinetically trapped 3D networks of fibrils. The propensity of disease-associated amyloid-forming peptides and proteins to assemble into polymorphic fibrils suggests that cross-β fibrils comprising...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nagy-Smith, Katelyn, Moore, Eric, Schneider, Joel, Tycko, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538636/
https://ncbi.nlm.nih.gov/pubmed/26216960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1509313112
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