Development of a Novel Formulation with Hypericin To Treat Cutaneous Leishmaniasis Based on Photodynamic Therapy in In Vitro and In Vivo Studies

An evaluation of the leishmanicidal activity in vitro and in vivo of hypericin, an expanded-spectrum photosensitizer found in Hypericum perforatum, is presented. Hypericin was evaluated against intracellular amastigotes in vitro of Leishmania (Viannia) panamensis. A topical formulation containing 0....

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Montoya, Andrés, Daza, Alejandro, Muñoz, Diana, Ríos, Karina, Taylor, Viviana, Cedeño, David, Vélez, Iván D., Echeverri, Fernando, Robledo, Sara M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538502/
https://ncbi.nlm.nih.gov/pubmed/26169411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00545-15
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