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In Vitro and In Vivo Studies of the Utility of Dimethyl and Diethyl Carbaporphyrin Ketals in Treatment of Cutaneous Leishmaniasis

Carbaporphyrin ketals are porphyrinoid compounds in which a pyrrole ring of a typical porphyrin macrocycle has been replaced by a ketal-substituted indene ring. It was recently demonstrated that these compounds are effective in vitro against Leishmania tarentolae. Their in vitro effectiveness is inc...

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Bibliographic Details
Main Authors: Taylor, Viviana M., Cedeño, David L., Muñoz, Diana L., Jones, Marjorie A., Lash, Timothy D., Young, Alexandra M., Constantino, Manuel H., Esposito, Nicholas, Vélez, Iván D., Robledo, Sara M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186979/
https://ncbi.nlm.nih.gov/pubmed/21788471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00671-11
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