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Kallistatin Ameliorates Influenza Virus Pathogenesis by Inhibition of Kallikrein-Related Peptidase 1-Mediated Cleavage of Viral Hemagglutinin

Proteolytic cleavage of the hemagglutinin (HA) of influenza virus by host trypsin-like proteases is required for viral infectivity. Some serine proteases are capable of cleaving influenza virus HA, whereas some serine protease inhibitors (serpins) inhibit the HA cleavage in various cell types. Kalli...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Leu, Chia-Hsing, Yang, Mei-Lin, Chung, Nai-Hui, Huang, Yen-Jang, Su, Yu-Chu, Chen, Yi-Cheng, Lin, Chia-Cheng, Shieh, Gia-Shing, Chang, Meng-Ya, Wang, Shainn-Wei, Chang, Yao, Chao, Julie, Chao, Lee, Wu, Chao-Liang, Shiau, Ai-Li
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538499/
https://ncbi.nlm.nih.gov/pubmed/26149981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00065-15
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