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Cleavage Activation of Human-adapted Influenza Virus Subtypes by Kallikrein-related Peptidases 5 and 12

A critical step in the influenza virus replication cycle is the cleavage activation of the HA precursor. Cleavage activation of influenza HA enables fusion with the host endosome, allowing for release of the viral genome into the host cell. To date, studies have determined that HA activation is driv...

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Detalhes bibliográficos
Main Authors: Hamilton, Brian S., Whittaker, Gary R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682540/
https://ncbi.nlm.nih.gov/pubmed/23612974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.440362
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