Correlation between GyrA Substitutions and Ofloxacin, Levofloxacin, and Moxifloxacin Cross-Resistance in Mycobacterium tuberculosis

The newer fluoroquinolones moxifloxacin (MXF) and levofloxacin (LVX) are becoming more common components of tuberculosis (TB) treatment regimens. However, the critical concentrations for testing susceptibility of Mycobacterium tuberculosis to MXF and LVX are not yet well established. Additionally, t...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Willby, Melisa, Sikes, R. David, Malik, Seidu, Metchock, Beverly, Posey, James E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538465/
https://ncbi.nlm.nih.gov/pubmed/26100699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00662-15
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