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High-Throughput Screening of Patient-Derived Cultures Reveals Potential for Precision Medicine in Glioblastoma

[Image: see text] Identifying drugs for the treatment of glioblastoma (GBM), a rapidly fatal disease, has been challenging. Most screening efforts have been conducted with immortalized cell lines grown with fetal bovine serum, which have little relevance to the genomic features found in GBM patients...

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Bibliografiske detaljer
Udgivet i:ACS Med Chem Lett
Main Authors: Quartararo, Christine E., Reznik, Eduard, deCarvalho, Ana C., Mikkelsen, Tom, Stockwell, Brent R.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2015
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538440/
https://ncbi.nlm.nih.gov/pubmed/26288699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00128
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