Glutamate Decarboxylase 67 Deficiency in a Subset of GABAergic Neurons Induces Schizophrenia-Related Phenotypes

Decreased expression of the GABA synthetic enzyme glutamate decarboxylase 67 (GAD67) in a subset of GABAergic neurons, including parvalbumin (PV)-expressing neurons, has been observed in postmortem brain studies of schizophrenics and in animal models of schizophrenia. However, it is unclear whether...

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Publicat a:Neuropsychopharmacology
Autors principals: Fujihara, Kazuyuki, Miwa, Hideki, Kakizaki, Toshikazu, Kaneko, Ryosuke, Mikuni, Masahiko, Tanahira, Chiyoko, Tamamaki, Nobuaki, Yanagawa, Yuchio
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538341/
https://ncbi.nlm.nih.gov/pubmed/25904362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.117
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