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Scavenger receptor class B, type I-mediated uptake of A1AT by pulmonary endothelial cells
In addition to exerting a potent anti-elastase function, α-1 antitrypsin (A1AT) maintains the structural integrity of the lung by inhibiting endothelial inflammation and apoptosis. A main serpin secreted in circulation by hepatocytes, A1AT requires uptake by the endothelium to achieve vasculoprotect...
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| Publicado no: | Am J Physiol Lung Cell Mol Physiol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4538232/ https://ncbi.nlm.nih.gov/pubmed/26092999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00376.2014 |
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