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A human laterality disorder associated with a homozygous WDR16 deletion

The laterality in the embryo is determined by left-right asymmetric gene expression driven by the flow of extraembryonic fluid, which is maintained by the rotary movement of monocilia on the nodal cells. Defects manifest by abnormal formation and arrangement of visceral organs. The genetic etiology...

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Detalles Bibliográficos
Publicado en:Eur J Hum Genet
Main Authors: Ta-Shma, Asaf, Perles, Zeev, Yaacov, Barak, Werner, Marion, Frumkin, Ayala, Rein, Azaria JJT, Elpeleg, Orly
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538206/
https://ncbi.nlm.nih.gov/pubmed/25469542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2014.265
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