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A human laterality disorder caused by a homozygous deleterious mutation in MMP21

BACKGROUND: Laterality in the vertebrate embryo is determined by left–right asymmetric gene expression driven by the flow of extraembryonic fluid across the embryonic node. Defects in these processes cause heterotaxy, the abnormal formation and arrangement of visceral organs that can range from comp...

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Dades bibliogràfiques
Publicat a:J Med Genet
Autors principals: Perles, Zeev, Moon, Sungjin, Ta-Shma, Asaf, Yaacov, Barak, Francescatto, Ludmila, Edvardson, Simon, Rein, Azaria JJT, Elpeleg, Orly, Katsanis, Nicholas
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936483/
https://ncbi.nlm.nih.gov/pubmed/26429889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2015-103336
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