Substance P induces cardioprotection in ischemia-reperfusion via activation of AKT

Accumulating evidence indicates that substance P is cardioprotective following ischemia-reperfusion primarily due to its potent coronary vasodilator actions. However, an anti-apoptotic effect of substance P has been observed in tenocytes following ischemia, which involved activation of the AKT pathw...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Jubair, Shaiban, Li, Jianping, Dehlin, Heather M., Manteufel, Edward J., Goldspink, Paul H., Levick, Scott P., Janicki, Joseph S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537946/
https://ncbi.nlm.nih.gov/pubmed/26071541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00200.2015
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