Non-human Primate and Rat Cardiac Fibroblasts show similar Extracellular Matrix-related and Cellular Adhesion Gene Responses to Substance P

BACKGROUND: The sensory nerve neuropeptide substance P (SP) regulates cardiac fibrosis in rodents under pressure overload conditions. Interestingly, SP induces transient increase expression of specific genes in isolated rat cardiac fibroblasts, without resultant changes in cell function. This sugges...

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Udgivet i:Heart Lung Circ
Main Authors: Meléndez, Giselle C., Manteufel, Edward J., Dehlin, Heather M., Register, Thomas C., Levick, Scott P.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4492475/
https://ncbi.nlm.nih.gov/pubmed/25550118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hlc.2014.11.015
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