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Incipient and overt stages of neoplastic transformation.

A subline of NIH 3T3 cells was developed that multiplies to low saturation density and produces no transformed foci in a standard assay at confluence if the cells had been kept in continuous exponential growth by passage at extremely low density. Repeated cycles of extended incubation at confluence...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Author: Rubin, H
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1994
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45379/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7991587/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.25.12076
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