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Phorbol-12-myristate-13-acetate is a potent enhancer of B cells with a granzyme B+ regulatory phenotype

IntroductionThe infusion of ex-vivo-generated regulatory B cells may represent a promising novel therapeutic approach for a variety of autoimmune and hyperinflammatory conditions including graft-versus-host disease.MethodsPreviously, we developed a protocol for the generation of a novel population o...

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Príomhchruthaitheoirí: Johanna Veh, Charlotte Mangold, Anja Felsen, Carolin Ludwig, Lisa Gerstner, Peter Reinhardt, Hubert Schrezenmeier, Dorit Fabricius, Bernd Jahrsdörfer
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Frontiers Media S.A. 2023-07-01
Sraith:Frontiers in Immunology
Ábhair:
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1194880/full
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