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Anti-hyperalgesic effects of imidazoline I(2) receptor ligands in a rat model of inflammatory pain: interactions with oxycodone

RATIONALE: Emerging preclinical evidence suggests that imidazoline I(2) receptor ligands may be effective analgesics. Quantitative analysis of the combined I(2) receptor ligands and opioids is needed for the justification of combination therapy. OBJECTIVE: This study systematically examined the anti...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Thorn, David A., Siemian, Justin N., Zhang, Yanan, Li, Jun-Xu
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537836/
https://ncbi.nlm.nih.gov/pubmed/26037946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-015-3983-1
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