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Anti-hyperalgesic effects of imidazoline I(2) receptor ligands in a rat model of inflammatory pain: interactions with oxycodone

RATIONALE: Emerging preclinical evidence suggests that imidazoline I(2) receptor ligands may be effective analgesics. Quantitative analysis of the combined I(2) receptor ligands and opioids is needed for the justification of combination therapy. OBJECTIVE: This study systematically examined the anti...

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Publicat a:Psychopharmacology (Berl)
Autors principals: Thorn, David A., Siemian, Justin N., Zhang, Yanan, Li, Jun-Xu
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537836/
https://ncbi.nlm.nih.gov/pubmed/26037946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-015-3983-1
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