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Structural mechanisms of plexin signaling

Signaling through plexin, the major cell surface receptor for semaphorin, plays critical roles in regulating processes such as neuronal axon guidance, angiogenesis and immune response. Plexin is normally kept inactive in the absence of semaphorin. Upon binding of semaphorin to the extracellular regi...

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Bibliographic Details
Published in:Prog Biophys Mol Biol
Main Authors: Pascoe, Heath G., Wang, Yuxiao, Zhang, Xuewu
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537802/
https://ncbi.nlm.nih.gov/pubmed/25824683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pbiomolbio.2015.03.006
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