CtBP1 over-expression in keratinocytes perturbs skin homeostasis

Carboxyl-terminal binding protein-1 (CtBP1) is a transcriptional co-repressor with multiple in vitro targets, but its in vivo functions are largely unknown. We generated keratinocyte-specific CtBP1 transgenic mice with a keratin 5 promoter (K5.CtBP1) to probe the pathological roles of CtBP1. At tran...

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Vydáno v:J Invest Dermatol
Hlavní autoři: Deng, Hui, Li, Fulun, Li, Hong, Deng, Yu, Liu, Jing, Wang, Donna, Han, Gangwen, Wang, Xiao-Jing, Zhang, Qinghong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537778/
https://ncbi.nlm.nih.gov/pubmed/24280726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2013.504
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