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Models of buffering of dosage imbalances in protein complexes
BACKGROUND: Stoichiometric imbalances in macromolecular complexes can lead to altered function. Such imbalances stem from under- or over-expression of a subunit of a complex consequent to a deletion, duplication or regulatory mutation of an allele encoding the relevant protein. In some cases, the ph...
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| 發表在: | Biol Direct |
|---|---|
| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4537584/ https://ncbi.nlm.nih.gov/pubmed/26275824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-015-0063-8 |
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